Identification and characterization of a novel single-chain variable fragment (scFv) antibody against Neisseria meningitidis factor H-binding protein (fHbp)
نویسندگان
چکیده
منابع مشابه
Bioinformatics prediction and experimental validation of VH antibody fragment interacting with Neisseria meningitidis factor H binding protein
Objective(s): We previously conducted an in silico research on the interactions between the ribosome display-selected single chain variable fragment (scFv) and factor H binding protein (fHbp) of Neisseria meningitidis. We found that heavy chain variable (VH) fragment of this scFv had considerable affinity to fHbp. These results led us to evaluate the ability of this sm...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 2018
ISSN: 0022-2615,1473-5644
DOI: 10.1099/jmm.0.000744